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New Cancer Breakthrough

New Cancer Breakthrough

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by: FoFa Active Indicator LED Icon 17 OP 
~ 10 years ago   Mar 24, '14 9:12am  
Researchers might have found the Holy Grail in the war against cancer, a miracle drug that has killed every kind of cancer tumor it has come in contact with, the New York Post reported.The drug works by blocking a protein called CD47 that is essentially a "do not eat" signal to the body's immune system, according to Science Magazine.This protein is produced in healthy blood cells, but researchers at Stanford University found that cancer cells produced an inordinate amount of the protein thus tricking the immune system into not destroying the harmful cells.With this observation in mind, the researchers built an antibody that blocked cancer's CD47 so that the body's immune system attacked the dangerous cells.So far, researchers have used the antibody in mice with human breast, ovary, colon, bladder, brain, liver and prostate tumors transplanted into them. In each of the cases the antibody forced the mice's immune system to kill the cancer cells. 4951
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EddyFree Active Indicator LED Icon 10
~ 10 years ago   Mar 24, '14 6:25pm  
Here's a picture of it:Loading Image... 4951
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TheTruthHurts Active Indicator LED Icon 12
~ 10 years ago   Mar 24, '14 8:28pm  
That's so exciting! 4951
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BooBear Active Indicator LED Icon 16
~ 10 years ago   Mar 24, '14 8:45pm  
It's time. Cancer sucks. 4951
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herron1345 Active Indicator LED Icon 16
~ 10 years ago   Mar 24, '14 8:58pm  
Like I mentioned in previous threads, cancer has taken many of my loved ones..........And caused so much heartache and pain........Cancer Is A Vicious Bastard........And I HATE IT....  ....And I pray that they do find a cure...........This is truly such wonderful and amazing news...May you live long, Die happy, And rate a mansion in heaven.  4951
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cgm10sne1 Active Indicator LED Icon 10
~ 10 years ago   Mar 24, '14 9:15pm  
yeah, but what happens if the "cure" goes onto the market? Do this cure hurt the Medical field? Sometimes I truly feel that they have always known a cure but trickle down the special medicines that do just that. How sad, even sadder is how this isn't on all the news channels???????. I'm snoping and hoping it's true info. 4951
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notfromhere Active Indicator LED Icon 12
~ 10 years ago   Mar 24, '14 10:14pm  
yeah, but what happens if the "cure" goes onto the market? Do this cure hurt the Medical field? Sometimes I truly feel that they have always known a cure but trickle down the special medicines that do just that. How sad, even sadder is how this isn't on all the news channels???????. I'm snoping and hoping it's true info.
 
@cgm10sne1: Why would you ever believe something like that? Cancer is extremely complex wih many contributing factors.
4951
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cgm10sne1 Active Indicator LED Icon 10
~ 10 years ago   Mar 25, '14 8:06am  
There have been many articles and information posted on the internet about many drugs that have "cured" certain Cancers. Of course you can't believe all the you read on the internet. I'm just saying that I've read where some drug companies have made major breakthrough with drugs but they never come available. If I suffered from Cancer I would want to be in a test study of any drug that could be helpful.  4951
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FoFa Active Indicator LED Icon 17 OP 
~ 10 years ago   Mar 25, '14 8:24am  
(1/14/14) Update on the anti-CD47 cancer therapy clinical trials Researchers and staff at Stanford are continuing to work hard preparing the groundwork for the clinical trials of our anti-CD47 antibody as a cancer therapy. We are anticipating the start of clinical trials sometime in the first half of this year, though unforeseen delays may yet slow that progress. As we get closer to the start of the clinical trials, we will be posting information about eligibility for the trials and how to apply.There has been a huge amount of interest in these trials from patients and their families and friends. However, we feel compelled to emphasize that, as is typical of FDA phase I clinical trials, the first tests of this therapy will be very small safety trials involving only a very few patients. Unfortunately, this means only a tiny fraction of those interested will be admitted to the first phase I clinical trials. Accordingly, we are urging patients to continue exploring existing treatments and other clinical trials. 4951
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WJo Active Indicator LED Icon 13
~ 10 years ago   Mar 25, '14 8:24am  
I  Heard this on the news about a week ago & was thrilled , but I'm wondering if this is all hype to keep us donating money to cancer research ? After all trillions upon trillions of dollars have been given to cancer research over the years & maybe the "big wigs" have decided it's time they let the cat out of the bag so we will continue to give them $$.I also heard on the same news cast that they have found a cure for Aids , but since that one announcement we have heard nothing , so what gives with that ? 4951
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analogkid Active Indicator LED Icon 3
~ 10 years ago   Mar 25, '14 8:40am  
I've worked in many different areas of cancer research beginning with immunobiology, antibody and ligand/receptor signaling, antibody drug conjugates (a burgeoning therapeutic area), most recently cancer metabolism, and now back to biologics/immunotherapy.  Lots of things kill cancer in mice.People like to complain about how meteorologists are lucky to work in a field when much of their production, i.e., forecasting the weather, is perceived to be frequently wrong.  If research worked on that premise, we'd have been out of jobs a long time ago.  We are wrong far, far more often than we are right and it's not for a lack of trying.  That's why it's called RE-search because even when something does go right, you get to RE-do it; certainly when something goes wrong you RE-do it as well, perhaps changing a/some variable(s).  Cancer cells are extremely "talented" at utilizing alternative or redundant signaling mechanisms and energy sources to survive, or expressing a protein on their cell membrane that allows it to elude immune detection.  It's an incredibly frustrating area to work in.  I've been at it for 21 years, mostly in biotech, and exactly two projects I've worked on have made it to patients, and another awaits phase I trial enrollment.  People like to make the claim that "they" have always known a cure or are holding something back.  I'd like to know who "they" are.  Pharma corporate elite?  Academic leaders in the field?  The people working at the bench or in the animal facility day-in and day-out?  I don't, in general, subscribe to conspiracy theory, but I know people do because it's the trivial solution for many questions.  Maybe there really is something going on in the boardroom of Pharma X Corporation but to think, at this point in time, that there is one common signaling component or one whack-a-mole hammer for all cancers is not paying enough respect to the biology and all of the complicating factors that  lead to the development and support of malignant growth. 4951
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analogkid Active Indicator LED Icon 3
~ 10 years ago   Mar 25, '14 8:50am  
I  Heard this on the news about a week ago & was thrilled , but I'm wondering if this is all hype to keep us donating money to cancer research ? After all trillions upon trillions of dollars have been given to cancer research over the years & maybe the "big wigs" have decided it's time they let the cat out of the bag so we will continue to give them $$.I also heard on the same news cast that they have found a cure for Aids , but since that one announcement we have heard nothing , so what gives with that ?
 
@WJo: Because news corps won't pay to have an informed, and objective, staff member that can vet out and provide a non-sensationalized version of a story that will still have to play out over the next decade's worth of clinical trials - if it is lucky enough to get that far.  
4951
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WJo Active Indicator LED Icon 13
~ 10 years ago   Mar 25, '14 8:55am  
there's always a "catch" to everything , isn't that true ? 4951
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